Patient with severe sepsis presents to the ITU.
Are we meeting the criteria suggested in the Surviving Sepsis Resuscitation bundles.
Retrospective audit of consecutive cases admitted to ITU with a diagnosis of sepsis ie. 2 or 4 SIRS Criteria and evidence of infection (highly suspicious of infection).
Resuscitation bundle defined as:
Serum lactate measured.
Blood cultures obtained prior to antibiotic administration.
From the time of presentation, broad-spectrum antibiotics administered within 3 hours for ED admissions and 1 hour for non-ED ICU admissions.
In the event of hypotension and/or lactate > 4mmol/L (36mg/dL):
Deliver an initial minimum of 20 ml/kg of crystalloid (or colloid equivalent)
Give vasopressors for hypotension not responding to initial fluid resuscitation to maintain mean arterial pressure (MAP) > 65 mm Hg.
In the event of persistent arterial hypotension despite volume resuscitation (septic shock) and/or initial lactate > 4 mmol/L (36 mg/dl):
Achieve central venous pressure (CVP) of > 8 mm Hg.
Achieve central venous oxygen saturation (ScvO2) of > 70% .*
Audit standard should be 95%.
More info at www.survivingsepsis.com
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